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Moreover, depending upon who you ask or where you get your information, the bioavailability of rectally-administered Hydromorphone (Dilaudid) is about 2x the potency of oral administration. If you've ever insufflated Hydromorphone, then you can expect a pretty similar experience to rectal administration. This aspect of Dilaudid Healthgrades Hydromorphone Hydrochloride Injection plays a vital role in practical applications.

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